Primary breast cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

In 2006 the estimated age-adjusted annual incidence of breast cancer in the European Union (25 countries) was 110.3/100 000 and the mortality 25.0/100 000. The incidence is increasing due to mammographic screening and aging population. The mortality rate has decreased especially in younger age groups because of earlier detection and improved treatment. However, breast cancer is still the leading cause of cancer-related deaths in European women.